Features of a new Coronavirus infection in children of different ages
https://doi.org/10.22627/2072-8107-2021-20-2-5-9
Abstract
The new coronavirus infection (COVID-1 9) is a socially significant problem around the world. According to available statistics, complications are less common among children, asymptomatic or mild forms of the disease prevail more often.
This article presents the features of the viral landscape of the upper respiratory tract in children with ARVI in a pandemic, the clinical and laboratory features of the course of COVID-1 9 in children of different ages.
It was found that SARS-CoV-2 is detected only in a third (32.9%) of hospitalized patients with respiratory symptoms, in 4.3% of cases — in combination with seasonal CoV-OC43 / CoV-229E, in 1 1.6% — with other respiratory viruses. The most frequent source of infection with the SARS-Cov-2 were family members. Children with a moderate form of the disease predominated among the patients. The leading symptoms of COVID-19 were fever, catarrhal symptoms, as well as gastrointestinal manifestations and anosmia. A feature of the new coronavirus infection in newborns and children of the first month of life was the absence of fever and intoxication, the lack of expression of catarrhal manifestations when the colon is involved in the pathological process (colitis, rarely — hemocolitis). In the compete blood test in children under the age of one year, monocytosis prevailed, in children over 7 years old — leukopenia and accelerated ESR. Among the changes in the biochemical analysis of blood, the most common was an increased C-reactive protein.
About the Authors
M. A. ShakmaevaRussian Federation
Maria Shakmaeva, full-time postgraduate student.
Saint-Petersburg
T. M. Chernova
Russian Federation
Tatyana Chernova, PhD, Associate Professor.
Saint-Petersburg
V. N. Timchenko
Russian Federation
Vladimir Timchenko, Professor, MD.
Saint-Petersburg
T. A. Nachinkina
Russian Federation
Tatyana Nachinkina, Chief physician.
Saint-Petersburg
K. V. Tetyushin
Russian Federation
Konstantin Tetyushin, Deputy Chief Physician.
Saint-Petersburg
T. A. Kaplina
Russian Federation
Tatyana Kaplina, PhD, Associate Professor.
Saint-Petersburg
M. D. Subbotina
Russian Federation
Maria Subbotina, PhD, Associate Professor.
Saint-Petersburg
O. V. Bulina
Russian Federation
Oksana Bulina, PhD, Associate Professor.
Saint-Petersburg
O. I. Afanasyeva
Russian Federation
Olga Afanasyeva, MD.
Saint-Petersburg
References
1. Ivanov D.O., Chernova T.M., Pavlova E.B., et al. Coronavirus infection. Pediatr. 2020. 11(3):109—117. (in Russ.)
2. Dondurei E.A., Isankina L.N., Afanasyeva O.I., Titeva A.V., Vishnevskaya T.V., Kondratyev V.A., Gryaznova I.A., Berezina M.V., Zolotova M A., Volzhanin VM. Characteristics of COVID-19 in children: the first experience of work in a hospital in St. Petersburg. Zhurnal Infektologii=Journal of Infectology 2020; 12(3):56—63 (in Russ.)
3. Zhou P., Yang X.L., Wang X.G., Hu B., Zhang L., Zhang W., et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 2020; 579(7798):270—273.
4. Timchenko V.N., Pavlova E.B., Mikhailov I.B., Khmilevskaya S.A. Diagnosis and Treatment of Childhood Infections. St. Petersburg, SpetsLit, 2020:476. (in Russ.)
5. Ivanova R.A., Skripchenko N.V, Vishnevskaya T.V, Isankina L.N., Prudova L.A., Piratova O.P., Minenok Yu.A., Katsieva L.Ya., Maisels M L., Shakmaeva M.A., Startseva Yu.V., Gaiduk M.K. COVID-19 in children in a metropolis: clinical, epidemiological and therapeutic aspects. Prakticheskaya Meditsina. 2020. 1 8(6): 1 19—127. (in Russ.)
6. Belan Yu.B., Gashina E.A., Lobova E., Bezrukova L.A. Coronavirus disease in children in the Omsk region. Detskie Infektsii=Children's Infections. 2020;19(4):30—33. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-4-30-33
7. She J, Liu L, Liu W. COVID-19 epidemic: Disease characteristics in children. J Med Virol. 2020 Jul;92(7):747—754
8. Interim guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19).» Version 11 (05/07/2021). 224 р. (in Russ.)
9. Dokhov M.A., Tikhomirova A.A., Vaulin G.F. Nonparametric criteria in the program «Statistica». Study guide. SPb.: SPbGPMU, 2019:40. (in Russ.)
10. Timchenko V.N., Sukhovetskaya V.F., Chernova T.M., Kaplina T.A., Subbotina M.D., Bulina O.V, Pisareva M.M. Results of 5-year monitoring of the circulation of seasonal coronaviruses in hospitalized children in the pre-pandemic period. Detskie Infektsii=Children's Infections. 2021; 20(1):5—11. (in Russ.) https://doi.org/10.22627/2072-8107-2021-20-1-5-11
11. Prevention, diagnosis and treatment of new coronavirus infection (COVID-19). Temporary guidelines. Version 7 (06/03/20). 165 p. (in Russ.)
Review
For citations:
Shakmaeva M.A., Chernova T.M., Timchenko V.N., Nachinkina T.A., Tetyushin K.V., Kaplina T.A., Subbotina M.D., Bulina O.V., Afanasyeva O.I. Features of a new Coronavirus infection in children of different ages. CHILDREN INFECTIONS. 2021;20(2):5-9. (In Russ.) https://doi.org/10.22627/2072-8107-2021-20-2-5-9