Clinical and prognostic significance of plasma fibronectin and circulating immune complexes in viral meningitis in children
https://doi.org/10.22627/2072-8107-2023-22-2-18-22
Abstract
The purpose of the study: to establish the clinical and prognostic value of fibronectin and circulating immune complexes of blood in children with viral meningitis, depending on the period, severity, course and outcome of the disease. Material and methods.The concentration of plasma fibronectin and the total amount of circulating immune complexes were determined by enzyme immunoassay in 167 children of patients with viral meningitis of various etiologies. The etiology of meningitis was confirmed by positive results of the PCR reaction and by enzyme immunoassay. The biological material for the study was: cerebrospinal fluid and/or blood. Results: In the acute period of moderate-severity viral meningitis, the concentration of fibronectin decreased and found.
About the Authors
O. G. Kimirilova
Аstrakhan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Аstrakhan
G. A. Kharchenko
Аstrakhan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Аstrakhan
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Review
For citations:
Kimirilova O.G., Kharchenko G.A. Clinical and prognostic significance of plasma fibronectin and circulating immune complexes in viral meningitis in children. CHILDREN INFECTIONS. 2023;22(2):18-22. (In Russ.) https://doi.org/10.22627/2072-8107-2023-22-2-18-22
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