Features of the course of whooping cough associated with rhinovirus and parainfluenza infections in a young child

Abstract

Purpose: to demonstrate a clinical case of whooping cough associated with rhinovirus and parainfluenza infections with an unfavorable outcome in a child 2 months of age. Results. The illness in the infant began acutely with the development of catarrhal syndrome in the form of a moderately expressed serous-mucous discharge from the nose, rare coughing, the addition of intoxication syndrome on the 2nd day (increase in body temperature to 39°C) and an increase in paroxysmal cough by the 5th day from the onset of the disease to 20 times a day, symptoms of respiratory failure. Based on clinical and laboratory data, a diagnosis was made: Whooping cough caused by Bordetella pertussis. Typical. Severe severity. PCR confirmed. Concomitant diagnosis: Viral infection of mixed etiology (Parainfluenza virus type 2, Human Rhinovirus). PCR confirmed. Complications: Community-acquired bilateral polysegmental pneumonia. Severe severity. Respiratory failure III degree. An unfavorable course of the disease was noted with the development of infectious toxic shock, disseminated intravascular coagulation syndrome and multiple organ failure, which led to death on the 12th day from the onset of the disease. This case convincingly shows that the combination of whooping cough with respiratory pathogens is the leading factor determining the complicated course and unfavorable outcome of the disease.